Depression is not something you can just snap out of or get over. It is a real medical condition. The first step is to understand facts about depression and to realize that you are not alone. Approximately one in six Americans experiences an episode of depression at some time during his/her adult life. Many who are depressed are not seeking treatment or getting the help they need.

Often, but not always, depression runs in families, and the course it takes is quite variable. Some people may only experience one significant depressive episode in their entire life, while others suffer with chronic depression that requires lifetime treatment.

The symptoms of depression are related to complex biochemical changes in the brain. Research evidence suggests that chemical messengers such as serotonin and norepinephrine lose their normal balance in areas of the brain that govern mood, pleasure, sleep, appetite and energy.

If these symptoms sound like you, you may be depressed:

  • Feelings of sadness, loneliness, hopelessness
  • Loss of interest or pleasure in activities
  • Changes in weight or appetite
  • Changes in sleep patterns
  • Feeling guilty or worthless
  • Difficulty concentrating, remembering things or making decisions
  • Fatigue or loss of energy
  • Restlessness or irritability
  • Thoughts of death or suicide
  • Headaches, joint pain, back/shoulder pain, stomach pain/indigestion
Summit Research Network is currently seeking individuals experiencing the above symptoms to participate in research studies of investigational medications for depression. If you are selected, all research-related care and study medications will be provided at no cost. If you would like more information on our current studies, please call us at one of the numbers listed above in the top right corner of the page, or fill out the form on the right and we will contact you.

Studies Related to Depression

There are many different kinds of depression, and depression can show itself in many different ways:
Condition We Study
Antidepressant Induced Sexual Dysfunction
Taking an antidepressant can negatively affect different aspects of your sex life.
Condition We Study
Feelings of excessive or irrational worry, feeling tense or edgy or battling unrealistic fears are symptoms of an anxiety disorder.
Condition We Study
Bipolar Disorder is characterized by extreme mood swings. People with bipolar disorder can be happy and elated at times, and then spiral into a deep depression.
Condition We Study
People with OCD experience constant irrational thoughts or fears that cause repetitive behaviors like hand washing, counting and ordering.
Condition We Study
Adolescent Depression
Depression in children is more than just the normal everyday emotions of growing up. Depressed children are persistently sad or may show disruptive behaviors at school or at home.
Currently Enrolling Seattle & Portland
PTSD can occur after someone has experienced a traumatic and/or terrifying event, such as a sexual or physical assault, the unexpected death of a loved one, or a natural disaster.
Condition We Study
Treatment Resistant Depression
Antidepressants aren't always enough for people suffering from depression. Some who take antidepressants don't get the relief they are looking for.
Condition We Study
depression2 (1)
Summit Research Network is offering free depression screenings all year long for adults and children as a part of National Depression Screening Day.